Sjogren's-Associated Diseases

Up to half of Sjogren's patients live with a second immune-mediated disease, often referred to as a "associated diseases".  Please see the Glossary for the definitions of immune-mediated, autoimmune, autoinflammatory, and comorbidity. 

Associated diseases include:

Autoimmune rheumatic diseases (AIRDs)- Sjogren's disease is part of the AIRD family, along with rheumatoid arthritis, systemic lupus erythematosus, and others. Sjogren's is sometimes called  "Secondary Sjogren's" by rheumatologists when patients have another AIRD.  See this blog post to learn why the term,"Secondary Sjogren's", should be discarded.
 

Autoinflammatory diseases such as several in the spondylitis family. Approximately 10% of Sjogren's patients have a version of  spondylitis, usually radiographic and non-radiographic axial spondylitis (aka, ankylosing and nR-axial spondylitis) and psoriatic arthritis (    ). Few clinicians are aware of this connection. 

 

Organ-specific autoimmune diseases, such as celiac disease and Hashimoto's thyroiditis. An estimated 7% of Sjogren's patients have celiac disease (), and 15-20% have Hashimoto's thyroiditis (). 

Resources

Notes   (put this at the end) 

 

AIRDs

ANon-immune mediated comorbidities such as cardiovascular disease or osteoporosis are considered to be general

Resources for direct Sjogren's features such as  sicca, neurological manifestations, organ involvement, or lymphoma are not  are not included on this page. Dysautonomia/POTS resources can be found here. 

The Sjogren's Foundation has many excellent brochures and videos on its website. 

Notes   (put this at the end) 

 

Autoinflammatory diseases
IANon-immune mediated comorbidities such as cardiovascular disease or osteoporosis are considered to be general

Resources for direct Sjogren's features such as  sicca, neurological manifestations, organ involvement, or lymphoma are not  are not included on this page. Dysautonomia/POTS resources can be found here. 

The Sjogren's Foundation has many excellent brochures and videos on its website. 

Notes   (put this at the end) 

 

Organ-specific autoimmune diseases
Autoinflammatory diseases

IANon-immune mediated comorbidities such as cardiovascular disease or osteoporosis are considered to be general

Resources for direct Sjogren's features such as  sicca, neurological manifestations, organ involvement, or lymphoma are not  are not included on this page. Dysautonomia/POTS resources can be found here. 

The Sjogren's Foundation has many excellent brochures and videos on its website. 

   (put this at the end) 

Non-immune mediated comorbidities such as cardiovascular disease or osteoporosis are considered to be general

Resources for direct Sjogren's features such as  sicca, neurological manifestations, organ involvement, or lymphoma are not  are not included on this page. Dysautonomia/POTS resources can be found here. 

The Sjogren's Foundation has many excellent brochures and videos on its website. 

Notes   (put this at the end) 

Functional disorders such as fibromyalgia, irritable bowel syndrome, and functional neurological disorders are usually inappropriate labels given to direct physcial manifestations of Sjogren's disease. 
See this blog post to learn more.

Non-immune mediated comorbidities such as cardiovascular disease or osteoporosis are considered to be general

Resources for direct Sjogren's features such as  sicca, neurological manifestations, organ involvement, or lymphoma are not  are not included on this page. Dysautonomia/POTS resources can be found here. 

The Sjogren's Foundation has many excellent brochures and videos on its website.