This section explains the correct approach to Sjogren’s diagnosis in adults. This information has helped many patients get diagnosed. I go into great detail because misperceptions about diagnosis are common.
You will read about barriers to diagnosis and how to counter incorrect information. Some clinicians inappropriately limit diagnosis to patients who meet the Classification Criteria, or worse, insist that patients must have Sjogren’s antibodies to be diagnosed. This leaves many people with Sjogren’s undiagnosed and untreated. Please read the Introduction to Diagnosis page first because it is important for understanding all of the other pages.
Classification Criteria are a useful research tool, but they are not diagnostic criteria. There are no diagnostic criteria at this time: Sjogren’s is a clinical diagnosis that takes into account many factors. Many Sjogren’s patients do not meet these criteria, especially early in the disease.
Learn about the core tests that used to help diagnose Sjogren’s. This section does not cover every test. It does not discuss tests that are used to monitor the disease.
Lists common presentations and the first steps that primary care providers (PCPs) can take to diagnose Sjogren’s. While this page is written with PCPs in mind, it is also helpful for patients and other clinicians
Salivary Gland Ultrasound
This test is increasingly being used at academic centers in place of the lip biopsy. The upside is that it is noninvasive. The reliability of this test, when utilized outside of academic medical centers, remains unknown. Like the lip biopsy, there are false positive and false negative results. I chose not to cover this test until it is more widely used and more is known.